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Can I read The effects of low-intensity ultrasound on peripheral nerve regeneration in poly(dl-lactic acid-co-glycolic acid) conduits seeded with Schwann cells on EtoBox?
The effects of low-intensity ultrasound on peripheral nerve regeneration in poly(dl-lactic acid-co-glycolic acid) conduits seeded with Schwann cells by Chen-Jung Chang; Shan-Hui Hsu is a Medicine article available to read on EtoBox.
What is The effects of low-intensity ultrasound on peripheral nerve regeneration in poly(dl-lactic acid-co-glycolic acid) conduits seeded with Schwann cells about?
This study attempted to improve the efficacy of peripheral nerve regeneration, using the stimulus of low-intensity ultrasound (US) on poly(DL-lactic acid-co-glycolic acid) (PLGA) nerve guidance conduits seeded with Schwann cells. The possible differences between the ultrasonic effects of biodegradable and nonbiodegradable materials used as conduits were also investigated, by comparison with a group of silicone conduits. The PLGA conduits were seeded with or without Schwann cells (6 ؋ 10 3 cells). All conduits were implanted 10 mm into right sciatic nerve defects in rats and underwent 12 ultrasonic treatment sessions over 2 weeks. Ultrasound was applied at a frequency of 1 MHz and an intensity of 0.2 W/cm 2 spatial average temporal peak (SATP) for 5 min/day. Histologic analysis was used to evaluate the recovery of the nerve after 6 weeks. Ultrasonically stimulated animals, especially those whose PLGA conduits, seeded with Schwann cells, exhibited considerably more myelinated axons with a larger mean area at the midconduit of the implanted grafts than those in any other group. Ultrasonic stimulation of a silicone conduit induced the generation of mass fibrous tissues that covered the
Who reads The effects of low-intensity ultrasound on peripheral nerve regeneration in poly(dl-lactic acid-co-glycolic acid) conduits seeded with Schwann cells?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Chen-Jung Chang; Shan-Hui Hsu
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0301-5629)
- Published
- 2004
- Language
- EN
- Field
- Medicine (Health Sciences)