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Pathomechanism of Intervertebral Disc Degeneration by Oichi, Takeshi; Taniguchi, Yuki; Oshima, Yasushi; Tanaka, Sakae; Saito, Taku is a Medicine article available to read on EtoBox.

What is Pathomechanism of Intervertebral Disc Degeneration about?

## Abstract Intervertebral disc degeneration (IDD) is the main contributor to low back pain, which is a leading cause of disability worldwide. Although substantial progress has been made in elucidating the molecular mechanisms of IDD, fundamental and long‐lasting treatments for IDD are still lacking. With increased understanding of the complex pathomechanism of IDD, alternative strategies for treating IDD can be discovered. A brief overview of the prevalence and epidemiologic risk factors of IDD is provided in this review, followed by the descriptions of anatomic, cellular, and molecular structure of the intervertebral disc as well as the molecular pathophysiology of IDD. Finally, the recent findings of intervertebral disc progenitors are reviewed and the future perspectives are discussed.

Who reads Pathomechanism of Intervertebral Disc Degeneration?

Author

Oichi, Takeshi; Taniguchi, Yuki; Oshima, Yasushi; Tanaka, Sakae; Saito, Taku

Publisher

Wiley (John Wiley & Sons); Wiley (ISSN 2572-1143)

Published

2020

Language

EN

Field

Medicine (Health Sciences)