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Can I read The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension on EtoBox?
The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension by Ludong Yuan; Yuting Tang; Leijing Yin; Xiaofang Lin; Zhengyang Luo; Shuxin Wang; Jing Li; Pengfei Liang; Bimei Jiang is a Medicine article available to read on EtoBox.
What is The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension about?
Transmembrane protein 16A (TMEM16A), a member of the TMEM16 family, is the molecular basis of Ca2 + -activated chloride channels (CaCCs) and is involved in a variety of physiological and pathological processes. Previous studies have focused more on respiratory-related diseases and tumors. However, recent studies have identified an important role for TMEM16A in cardiovascular diseases, especially in pulmonary hypertension. TMEM16A is expressed in both pulmonary artery smooth muscle cells and pulmonary artery endothelial cells and is involved in the development of pulmonary hypertension. This paper presents the structure and function of TMEM16A, the pathogenesis of pulmonary hypertension, and highlights the role and mechanism of TMEM16A in pulmonary hypertension, summarizing the controversies in this field and taking into account hypertension and portal hypertension, which have similar pathogenesis. It is hoped that the unique role of TMEM16A in pulmonary hypertension will be illustrated and provide ideas for research in this area.
Who reads The role of Transmembrane Protein 16A (TMEM16A) in pulmonary hypertension?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ludong Yuan; Yuting Tang; Leijing Yin; Xiaofang Lin; Zhengyang Luo; Shuxin Wang; Jing Li; Pengfei Liang; Bimei Jiang
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)