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Can I read Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production on EtoBox?

Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production by Tetsuta Oshitari; Yuji Okuyama; Yoshiki Miyata; Hiroshi Kosano; Hideyo Takahashi; Hideaki Natsugari is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production about?

A divergent synthesis of nobiletin metabolites was developed through highly oxygenated acetophenone derivative. We used commercially available methyl 3,4,5-trimethoxybenzoate as a starting material for concise preparation of the key intermediate, 2'-hydroxy-3',4',5',6'-tetramethoxyacetophenone (I). These metabolites showed strong inhibitory activity against matrix metalloproteinase-9 production in human lens epithelial cells.

Who reads Nobiletin metabolites: Synthesis and inhibitory activity against matrix metalloproteinase-9 production?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Tetsuta Oshitari; Yuji Okuyama; Yoshiki Miyata; Hiroshi Kosano; Hideyo Takahashi; Hideaki Natsugari
Publisher
Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
Published
2011
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)