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Study protocol: the ILANA study – exploring optimal implementation strategies for long-acting antiretroviral therapy to ensure equity in clinical care and policy for women, racially minoritised people and older people living with HIV in the UK – a qualitative multiphase longitudinal study design by Farooq, Hamzah Z (author);Apea, Vanessa (author);Kasadha, Bakita (author);Ullah, Sadna (author);Hilton-Smith, Gill (author);Haley, Amber (author);Scherzer, Jenny (author);Hand, James (author);Paparini, Sara (author);Phillips, Rachel (author);Orkin, Chloe M (author) is a Medicine article available to read on EtoBox.

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## Introduction Cabotegravir and rilpivirine (CAB+RPV long-acting (LA)) is recommended as a treatment for HIV-1 allowing people living with HIV to receive 2 monthly injectable treatment, rather than daily pills. Providing injectable therapy in a system designed to provide and manage study participants on oral treatments poses logistical challenges namely how resources are used to accommodate patient preference within constrained health economies with capacity limitations. In this pragmatic multicentre study, we aim to understand the implementation of CAB-RPV-LA administration in two settings via mixed methods to explore perspectives of participants and the clinical team delivering CAB+RPV LA. ## Methods and analysis Women, racially minoritised people and older people are chronically under-represented in HIV clinical trials so the ILANA trial has set recruitment caps to ensure recruitment of 50% women, 50% ethnically diverse people and 30% over 50 years of age to include a more representative study population. Using a mixed-methods approach, the primary objective is to identify and evaluate the critical implementation strategies for CAB+RPV LA in both hospital and community settings

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Author

Farooq, Hamzah Z (author);Apea, Vanessa (author);Kasadha, Bakita (author);Ullah, Sadna (author);Hilton-Smith, Gill (author);Haley, Amber (author);Scherzer, Jenny (author);Hand, James (author);Paparini, Sara (author);Phillips, Rachel (author);Orkin, Chloe M (author)

Publisher

BMJ

Published

2023

Language

EN

Field

Medicine (Health Sciences)