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Post mortem magnetic resonance imaging in the fetus, infant and child: A comparative study with conventional autopsy (MaRIAS Protocol) by Sudhin Thayyil; Neil J Sebire; Lyn S Chitty; Angie Wade; Oystein Olsen; Roxana S Gunny; Amaka Offiah; Dawn E Saunders; Catherine M Owens; WK 'Kling' Chong; Nicola J Robertson; Andrew M Taylor is a Medicine article available to read on EtoBox.
What is Post mortem magnetic resonance imaging in the fetus, infant and child: A comparative study with conventional autopsy (MaRIAS Protocol) about?
## Background Minimally invasive autopsy by post mortem magnetic resonance (MR) imaging has been suggested as an alternative for conventional autopsy in view of the declining consented autopsy rates. However, large prospective studies rigorously evaluating the accuracy of such an approach are lacking. We intend to compare the accuracy of a minimally invasive autopsy approach using post mortem MR imaging with that of conventional autopsy in fetuses, newborns and children for detection of the major pathological abnormalities and/or determination of the cause of death. ## Methods/Design We recruited 400 consecutive fetuses, newborns and children referred for conventional autopsy to one of the two participating hospitals over a three-year period. We acquired whole body post mortem MR imaging using a 1.5 T MR scanner (Avanto, Siemens Medical Solutions, Enlargen, Germany) prior to autopsy. The total scan time varied between 90 to 120 minutes. Each MR image was reported by a team of four specialist radiologists (paediatric neuroradiology, paediatric cardiology, paediatric chest & abdominal imaging and musculoskeletal imaging), blinded to the autopsy data. Conventional autopsy was performe
Who reads Post mortem magnetic resonance imaging in the fetus, infant and child: A comparative study with conventional autopsy (MaRIAS Protocol)?
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- Author
- Sudhin Thayyil; Neil J Sebire; Lyn S Chitty; Angie Wade; Oystein Olsen; Roxana S Gunny; Amaka Offiah; Dawn E Saunders; Catherine M Owens; WK 'Kling' Chong; Nicola J Robertson; Andrew M Taylor
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-2431)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)