About this document
Efficient Synthesis of Pyrrolines via Catalysis by ssawaquiapeg is a document available to read on EtoBox.
This paper describes an efficient method for synthesizing N-aryl and N-alkyl pyrrolines using palladium-catalyzed allylation of amines with allyl alcohols, followed by ring-closing metathesis. The process allows for the recycling of excess allyl alcohol and demonstrates high yields, including a one-pot reaction that achieved 95% yield of N-phenyl pyrroline. The study highlights the influence of electronic and steric properties of amines on the reaction efficiency and provides a broad substrate scope for var
- Author
- ssawaquiapeg
- Language
- EN