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Secondary hematopoietic malignancies in survivors of childhood cancer : An analysis of 111 cases from the Surveillance, Epidemiology, and End Result-9 registry by Rawad Rihani; Faiha Bazzeh; Nesreen Faqih; Iyad Sultan is a Medicine article available to read on EtoBox.

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## Abstract ## BACKGROUND: Studying secondary hematological malignancies in a large cohort of patients can help predict risks and trends associated with current therapies. ## METHODS: The authors analyzed data from the Surveillance, Epidemiology, and End Resultsecondary 9 (SEER‐9) database on patients with a primary malignancy (diagnosed before the age of 20 years) between 1973 and 2005 who developed a secondary hematological malignancy. Primary cancer and histological subtype, incidence, risk factors, outcomes, and changes in risk patterns of secondary hematological malignancies were analyzed for 1973 to 1985, 1986 to 1995, and 1996 to 2005. Standardized incidence ratios (SIRs) of observed to expected cancers were calculated. ## RESULTS: Of 34,867 patients with a histology‐confirmed primary malignancy, 111 developed secondary hematological malignancies (median, 44 months). Lymphoma was the commonest primary cancer (n = 47). The main histological subtype of secondary hematological malignancy was acute myeloid leukemia (AML) (49%), which had the shortest median latency time and the worst 5‐year survival (18% ± 5.3%; __P__ = .044). Secondary Hodgkin lymphoma had the best 5‐year survi

Who reads Secondary hematopoietic malignancies in survivors of childhood cancer : An analysis of 111 cases from the Surveillance, Epidemiology, and End Result-9 registry?

Author

Rawad Rihani; Faiha Bazzeh; Nesreen Faqih; Iyad Sultan

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

2010

Language

EN

Field

Medicine (Health Sciences)