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Can I read The genetic basis of inhibitor development in haemophilia A on EtoBox?
The genetic basis of inhibitor development in haemophilia A by C. A. Lee; C. M. Kessler; D. Varon; U. Martinowitz; M. Heim; E. G. D. TUDDENHAM; J. H. MCVEY is a Medicine article available to read on EtoBox.
What is The genetic basis of inhibitor development in haemophilia A about?
Summary. Inhibitor development is now the main complication of replacement therapy in haemophilia A. Given that most severely affected patients make no detectable factor VIII, it is perhaps surprising that only ̃30% actually mount an immune response to factor VIII as a foreign antigen. Those that do mostly have major factor VIII gene lesions. The association of HLA genotype with inhibitors in patients with identical mutations is weak. Environmental factors may be more important than genetic in antibody response to factor VIII.
Who reads The genetic basis of inhibitor development in haemophilia A?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- C. A. Lee; C. M. Kessler; D. Varon; U. Martinowitz; M. Heim; E. G. D. TUDDENHAM; J. H. MCVEY
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 1351-8216)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Health Sciences)