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This review discusses the role of pathogen-derived nucleases in evading the immune response by degrading extracellular traps (ETs) produced by host immune cells. It highlights various bacterial, fungal, and parasitic pathogens that utilize nucleases to dismantle the DNA backbone of ETs, thereby enhancing their pathogenicity. The document summarizes key findings on specific nucleases and their mechanisms of action in different pathogens, emphasizing their significance in immune evasion strategies.
- Author
- jeanflorentbikoi
- Language
- EN