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Glomeruloid hemangioma –- a specific cutaneous marker of POEMS syndrome by Rubem David Azulay; Ignez Regina Muri Mendonça; Cristiane Marcia Santos; Paulo Cesar Fialhomonteiro Monteiro; Marcia Santos Lazéra; Bernardo Kawa Kac; Regina Casz Schechtman is a Medicine article available to read on EtoBox.

What is Glomeruloid hemangioma –- a specific cutaneous marker of POEMS syndrome about?

A 65‐year‐old Brazilian man presented with an erythematous nodular lesion on the left forearm (Fig. 1). The patient had been treated with multidrug therapy for 8 months for lepromatous leprosy. During therapy, he developed recurrent episodes of reactions which were treated with high doses of prednisone and thalidomide. The histopathology of the cutaneous nodular lesion showed a granulomatous inflammatory infiltrate; some histiocytes contained vacuolations and others demonstrated oval‐like or coma‐like structures (Fig. 2). The specimen was cultivated in Sabouraud agar at room temperature. The colonies were transferred to Petri dishes containing Niger Seed Agar (NSA) (Fig. 3). The confirmed diagnosis was __Cryptococcus neoformans__ var. __neoformans__ based on microscopy and physiology, including the canavanine–glycine–bromothymol blue (CGB) medium (Lazéra MS, Pires FDA, Camillo‐Coura L __et al__. Natural habitat of __Cryptococcus neoformans__ var. __neoformans__ in decaying wood forming hollows in living trees. __J Med Vet Mycol__ 1996; **34:** 127–131). The liquor culture was negative. Hemoculture and urine culture were also negative. Latex agglutination test was blood positive and

Who reads Glomeruloid hemangioma –- a specific cutaneous marker of POEMS syndrome?

Author

Rubem David Azulay; Ignez Regina Muri Mendonça; Cristiane Marcia Santos; Paulo Cesar Fialhomonteiro Monteiro; Marcia Santos Lazéra; Bernardo Kawa Kac; Regina Casz Schechtman

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0011-9059)

Published

2001

Language

EN

Field

Medicine (Health Sciences)