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White Matter Plasticity in Reading-Related Pathways Differs in Children Born Preterm and at Term: A Longitudinal Analysis by Lisa Bruckert; Lauren R. Borchers; Cory K. Dodson; Virginia A. Marchman; Katherine E. Travis; Michal Ben-Shachar; Heidi M. Feldman is a Engineering article available to read on EtoBox.

Children born preterm (PT) are at risk for white matter injuries based on complications of prematurity. They learn to read but on average perform below peers born full term (FT). Studies have yet to establish whether properties of white matter pathways at the onset of learning to read are associated with individual variation later in reading development in PT children. Here, we asked whether fractional anisotropy (FA) at age 6 years is associated with reading outcome at age 8 years in PT children in the same pathways as previously demonstrated in a sample of FT children. PT ( = 34, mean gestational age = 29.5 weeks) and FT children ( = 37) completed diffusion MRI and standardized measures of non-verbal IQ, language, and phonological awareness at age 6 years. Reading skills were assessed at age 8 years. Mean tract-FA was extracted from pathways that predicted reading outcome in children born FT: left arcuate fasciculus (Arc), bilateral superior longitudinal fasciculus (SLF), and left inferior cerebellar peduncle (ICP). We explored associations in additional pathways in the PT children: bilateral inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, and uncinate fas

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Author
Lisa Bruckert; Lauren R. Borchers; Cory K. Dodson; Virginia A. Marchman; Katherine E. Travis; Michal Ben-Shachar; Heidi M. Feldman
Publisher
Frontiers; Frontiers Media SA; Frontiers Media S.A.; Lausanne: Frontiers Media S.A., 2008- (ISSN 1662-5161)
Published
2019
Language
EN
Field
Engineering (Physical Sciences)