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Can I read Short and Long-term Metabolic Outcomes in Patients with Type 1 and Type 2 Diabetes Receiving a Simultaneous Pancreas Kidney Allograft on EtoBox?

Short and Long-term Metabolic Outcomes in Patients with Type 1 and Type 2 Diabetes Receiving a Simultaneous Pancreas Kidney Allograft by Hau, Hans-Michael; Jahn, Nora; Brunotte, Maximilian; Lederer, Andri Arnosson; Sucher, Elisabeth; Rasche, Franz Maximilian; Seehofer, Daniel; Sucher, Robert is a Medicine article available to read on EtoBox.

What is Short and Long-term Metabolic Outcomes in Patients with Type 1 and Type 2 Diabetes Receiving a Simultaneous Pancreas Kidney Allograft about?

## Background In contrast to insulin-dependent type 1 diabetes mellitus (T1DM), the indication for Simultaneous pancreas-kidney transplantation (SPK) in patients with type 2 diabetes mellitus (T2DM) is still ambiguous and wisely Eurotransplant (ET) only granted transplant-permission in a selected group of patients. However, with regard to improvement of metabolic conditions SPK might still be a considerable treatment option for lean insulin dependent type 2 diabetics suffering from renal disease. ## Methods Medical data (2001–2013) from all consecutive T1DM and T2DM patients who received a SPK or kidney transplant alone (KTA) at the University Hospital of Leipzig were analyzed. Donor, recipients and long-term endocrine, metabolic and graft outcomes were investigated for T1DM and T2DM-SPK recipients (transplanted upon a special request allocation by ET) and T2DM patients who received a KTA during the same period. ## Results Eighty nine T1DM and 12 T2DM patients received a SPK and 26 T2DM patients received a KTA. Patient survival at 1 and 5 years was 89.9 and 88.8% for the T1DM group, 91.7 and 83.3% for the T2DM group, and 92.3 and 69.2% for the T2DM KTA group, respectively (__p < 0.

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Author
Hau, Hans-Michael; Jahn, Nora; Brunotte, Maximilian; Lederer, Andri Arnosson; Sucher, Elisabeth; Rasche, Franz Maximilian; Seehofer, Daniel; Sucher, Robert
Publisher
BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1472-6823)
Published
2020
Language
EN
Field
Medicine (Health Sciences)