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Comparison of Two Platelet Additive Solutions by P. F. Van Der Meer; R. N. I. Pietersz; H. W. Reesink is a Medicine article available to read on EtoBox.

What is Comparison of Two Platelet Additive Solutions about?

. The use of an additive solution for substitution of plasma for storage of leukodepleted platelet concentrates can have many advantages. In this study, a comparison was made between two platelet additive solutions: one containing citrate and acetate (PAS‐II), the other also supplemented with additional salts such as magnesium, and with gluconate (Composol‐PS). Donor‐dependent differences were avoided by applying a paired experimental design (__n__ = 10). The platelet concentrates were prepared by pooling five buffy coats and the additive solution, and prestorage filtration was utilized to remove leucocytes to well below 1 × 10^6^. Storage of platelet concentrates up to 9 days after blood collection revealed that platelet concentrates in Composol‐PS maintained an almost constant pH of on average 6·93 from day 2 through day 7, and at 6·90 at day 9. This was in contrast to PAS‐II, which showed a gradually decreasing pH from on average 6·97 at day 1 to 6·86 at day 9. In all units stored in both solutions the swirling effect was present during 9 days of storage. In conclusion, both additive solutions allow storage of platelets, derived from pooled buffy coats, for up to 9 days after co

Who reads Comparison of Two Platelet Additive Solutions?

Author

P. F. Van Der Meer; R. N. I. Pietersz; H. W. Reesink

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0958-7578)

Published

2001

Language

EN

Field

Medicine (Health Sciences)