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LQ Model vs. BED in High-Dose Irradiation by Gedeon Motsa is a document available to read on EtoBox.
This study evaluates the compatibility of the linear-quadratic (LQ) model and biologically effective dose (BED) concept in high-dose-per-fraction irradiation using a murine tumor model. Results indicate that the LQ formalism underestimates the in vivo effects of hypofractionated radiation by approximately 20%-40%, with discrepancies increasing with the number of fractions. The findings suggest that BED may not be a reliable measure of tumor response in this context.
- Author
- Gedeon Motsa
- Language
- EN