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What is Primary Graft Failure in AML Transplants about?

This study analyzed primary graft failure (pGF) outcomes in 2497 acute myeloid leukemia patients undergoing unrelated hematopoietic stem cell transplantation with post-transplant cyclophosphamide (PTCy). The incidence of pGF was found to be 5.6%, with 70.9% of those who failed to engraft by day +30 achieving recovery by day +60. Factors such as ANC recovery, Karnofsky performance status, and being in complete remission at the time of HSCT were associated with improved overall survival post-pGF.

Author

dr.solankids

Language

EN