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Can I read Tirbanibulina: Revisión de Su Mecanismo de Acción Novedoso Y de Cómo Encaja En el Tratamiento de la Queratosis Actínica on EtoBox?
Tirbanibulina: Revisión de Su Mecanismo de Acción Novedoso Y de Cómo Encaja En el Tratamiento de la Queratosis Actínica by Y. Gilaberte; M.T. Fernández-Figueras is a Medicine article available to read on EtoBox.
What is Tirbanibulina: Revisión de Su Mecanismo de Acción Novedoso Y de Cómo Encaja En el Tratamiento de la Queratosis Actínica about?
Actinic keratosis (AK) is a skin condition characterized by the proliferation of mutated keratinocytes that can develop into squamous cell carcinoma. Available therapies, although effective, are associated with a high frequency of severe local skin reactions. Tirbanibulin, one of the treatments for AK currently in development, is a new synthetic chemical entity with anti-proliferative and anti-tumor effects, both in vitro and in vivo, with proved efficacy in the treatment of AK, which has been recently demonstrated in two phase III clinical trials. In the present review, the tirbanibulin mechanism of action, based on the relevant literature and the results of several unpublished preclinical studies, is shown. In addition, the current scenario regarding the available treatments and how the novel tirbanibulin mechanism of action fits into the treatment of AK is raised.
Who reads Tirbanibulina: Revisión de Su Mecanismo de Acción Novedoso Y de Cómo Encaja En el Tratamiento de la Queratosis Actínica?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Y. Gilaberte; M.T. Fernández-Figueras
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- ES
- Field
- Medicine (Health Sciences)