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Sunflower-Like Nanostructure with Built-In Hotspots for Alpha-Fetoprotein Detection by Zhao, Xiaoyu (author);Zhu, Aonan (author);Wang, Yaxin (author);Zhang, Yongjun (author);Zhang, Xiaolong (author) is a Chemistry article available to read on EtoBox.

What is Sunflower-Like Nanostructure with Built-In Hotspots for Alpha-Fetoprotein Detection about?

In the present study, a sunflower-like nanostructure array composed of a series of synaptic nanoparticles and nanospheres was manufactured through an efficient and low-cost colloidal lithography technique. The primary electromagnetic field contribution generated by the synaptic nanoparticles of the surface array structures was also determined by a finite-difference time-domain software to simulate the hotspots. This structure exhibited high repeatability and excellent sensitivity; hence, it was used as a surface-enhanced Raman spectroscopy (SERS) active substrate to achieve a rapid detection of ultra-low concentrations of Alpha-fetoprotein (AFP). This study demonstrates the design of a plasmonic structure with strong electromagnetic coupling, which can be used for the rapid detection of AFP concentration in clinical medicine.

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Author

Zhao, Xiaoyu (author);Zhu, Aonan (author);Wang, Yaxin (author);Zhang, Yongjun (author);Zhang, Xiaolong (author)

Publisher

MDPI AG

Published

2021

Language

EN

Field

Chemistry (Life Sciences)