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Herpes folliculitis: clinical, histopathological, and molecular pathologic observations: Herpes folliculitis: diagnostic criteria by A. Böer; N. Herder; K. Winter; T. Falk is a Medicine article available to read on EtoBox.

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## Background: Herpes folliculitis is a rare manifestation of herpes virus infection and it is often misdiagnosed. diagnostic criteria are not well established, only 24 patients being reported in the literature. recently it has been suggested that herpetic folliculitis is more common in infections with varicella zoster (vzv) than in those with herpes simplex viruses (hsv-1 and -2). ## Objectives: To refine diagnostic criteria for folliculitis caused by vzv, hsv-1 and hsv-2, and to study whether follicular involvement enables morphological differentiation between vzv and hsv infections. ## Patients and methods: Twenty-one patients with herpetic infection of follicular epithelium were assessed clinically and histopathologically. polymerase chain reaction (pcr) studies for specific dna of herpes viruses were performed on paraffin-embedded biopsy specimens. ## Results: In 17 of our cases pcr was positive for vzv, four were positive for hsv-1, none for hsv-2. the clinical presentation of herpes folliculitis often lacked vesicles or pustules (14/21). histopathological features were often devoid of ballooning (12/21), multinucleated giant cells (12/21) and keratinocytes with steel grey nu

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Author

A. Böer; N. Herder; K. Winter; T. Falk

Publisher

Oxford University Press (OUP)

Published

2006

Language

EN

Field

Medicine (Health Sciences)