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Corticospinal Output and Cortical Excitation‐inhibition Balance in Distal Hand Muscle Representations in Nonprimary Motor Area by Selja Vaalto; Laura Säisänen; Mervi Könönen; Petro Julkunen; Taina Hukkanen; Sara Määttä; Jari Karhu is a Neuroscience article available to read on EtoBox.

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## Abstract Transcranial magnetic stimulation (TMS) of the superior frontal gyrus in the non‐primary motor area (NPMA) can evoke motor‐evoked potentials (MEPs) at 20 ms latency range in contralateral distal hand muscles similar to stimulation of M1 and indicating monosynaptic corticospinal tracts. We compared the intracortical inhibitory and excitatory balance in primary motor cortex (M1) and in NPMA by navigated single‐ and paired‐pulse TMS (ppTMS). We also evaluated the spatial stability of muscle representations in M1 and NPMA by remapping 11 healthy subjects one year after the initial mapping. Resting motor threshold (rMT) was higher in NPMA than in M1 as were the MEP amplitudes evoked by 120% rMT stimulation intensity of the local MT. Short‐interval intracortical inhibition (SICI) was significantly weaker in NPMA than in M1 at ISI of 2 ms and conditioning stimulus (CS) 80% rMT. Our findings suggest that the cortical hand representations in NPMA 1) are connected to lower motoneurons monosynaptically, 2) are less strictly organized, i.e. motoneuron population representing a discrete hand muscle is sparser and less dense than in M1 and 3) have the capacity to generate powerful, r

Who reads Corticospinal Output and Cortical Excitation‐inhibition Balance in Distal Hand Muscle Representations in Nonprimary Motor Area?

Author

Selja Vaalto; Laura Säisänen; Mervi Könönen; Petro Julkunen; Taina Hukkanen; Sara Määttä; Jari Karhu

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 1065-9471)

Published

2010

Language

EN

Field

Neuroscience (Life Sciences)