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This review discusses the increasing prevalence of bloodstream infections caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E) and the challenges posed by carbapenem resistance. It recommends using carbapenems, specifically meropenem and imipenem, for serious infections, while suggesting carbapenem-sparing alternatives like piperacillin/tazobactam for milder cases. The review highlights the need for optimized dosing and cautious use of newer antibiotics as last-resort options.

Author

jacksparrow7425

Language

EN