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Effect of Antidepressant Use on Admissions to Hospital Among Elderly Bipolar Patients by Ayal Schaffer; Muhammad Mamdani; Anthony Levitt; Nathan Herrmann is a Medicine article available to read on EtoBox.

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## Abstract ## Objective The goal of this study was to examine the association between antidepressant use and hospitalization rate for mania or bipolar depression in a large, community‐based sample of elderly bipolar patients. ## Method Population‐based retrospective cohort design. Administrative healthcare databases were linked for all individuals aged 66 years or older in the Province of Ontario, Canada. Bipolar subjects who received a prescription for an antidepressant medication (__n__ = 1,072) between 1 April 1997 and 31 March 2001 comprised the antidepressant cohort. The control group (__n__ = 3,000) consisted of randomly selected subjects from the eligible bipolar population who did not receive a prescription for an antidepressant medication during the same surveillance period. Primary outcomes were admission to hospital for a manic/mixed or depressive episode. ## Results During a total of 5135 person‐years of follow up, 113 admissions for a manic/mixed episode and 28 admissions for a depressive episode were identified. Model based estimates adjusted for a number of covariates revealed that, as compared with the control group, the antidepressant cohort had significantly lowe

Who reads Effect of Antidepressant Use on Admissions to Hospital Among Elderly Bipolar Patients?

Author

Ayal Schaffer; Muhammad Mamdani; Anthony Levitt; Nathan Herrmann

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0885-6230)

Published

2006

Language

EN

Field

Medicine (Health Sciences)