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Use of Ball Milling for the Synthesis of Biologically Active Heterocycles by Nirmalya Mukherjee; Pintu Maity; Brindaban C. Ranu is a book available to read on EtoBox.

What is Use of Ball Milling for the Synthesis of Biologically Active Heterocycles about?

The technological and scientific challenges coupled with environmental concern have prompted interest in simple, eco-friendly, and energy-efficient procedures for the synthesis of biologically active molecules and materials. During the last decade, ball milling has emerged as a powerful tool in effecting chemical transformations in a greener way. However, mechanochemical synthesis, which involves reactions conducted by grinding solid reactants with no or minimal solvent in a ball mill, is less explored in comparison to other techniques such as microwave and ultrasound. Remarkably, during the last 5 years the interest in this technique grew tremendously because of its several advantages toward development of sustainable methods. Thus ball mill has become a regular tool in academy and industry. On the other hand, heterocyclic compounds occupy a major space in the domain of modern medicines. Thus development of an efficient methodology for the synthesis of heterocyclic molecules is always a center of interest for synthetic organic chemists. This chapter gives an overview of the application of ball milling for the synthesis of biologically active heterocycles highlighting the recent de

Author

Nirmalya Mukherjee; Pintu Maity; Brindaban C. Ranu

Publisher

Elsevier

Published

2021

Language

EN