Can I read Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance on EtoBox?

Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance by Nawrocki, Steffan T.; Wang, Wei; Carew, Jennifer S. is a Medicine article available to read on EtoBox.

What is Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance about?

Autophagy is a mechanism of lysosomal proteolysis that is utilized to degrade damaged organelles, proteins, and other cellular components. Although key studies demonstrate that autophagy functions as a mechanism of tumor suppression via the degradation of defective pre-malignant cells, autophagy can also be used as a mechanism to break down cellular components under stress conditions to generate the required metabolic materials for cell survival. Autophagy has emerged as an important mediator of resistance to radiation, chemotherapy, and targeted agents. This series of articles highlight the role of autophagy in cancer progression and drug resistance and underscores the need for new and more effective agents that target this process.

Who reads Autophagy: New Insights into Its Roles in Cancer Progression and Drug Resistance?

Author

Nawrocki, Steffan T.; Wang, Wei; Carew, Jennifer S.

Publisher

MDPI AG; Multidisciplinary Digital Publishing Institute (MDPI); Basel: MDPI, 2009- (ISSN 2072-6694)

Published

2020

Language

EN

Field

Medicine (Health Sciences)