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Long-term results of irradiation for patients with progressive GRAVES’ ophthalmopathy by Sheri D Marquez; Bert L Lum; I.Ross McDougall; Shobha Katkuri; Peter S Levin; Michael MacManus; Sarah S Donaldson is a Medicine article available to read on EtoBox.

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## Purpose: To determine the long-term outcome of radiotherapy (rt) in patients with progressively symptomatic thyroid eye disease and to evaluate the potential long-term sequelae. ## Methods and materials: Four hundred fifty-three patients provided written informed consent and received retrobulbar rt for graves' ophthalmopathy at stanford university medical center; 197 with 1 year of follow-up were retrospectively analyzed. of the 197 patients, 189 received rt to the bilateral retrobulbar regions, and 4 received unilateral rt. the technical information was unavailable for 4 patients. patients were assessed by chart review, telephone interview, questionnaire, and multidisciplinary physician examination. eye impairment was scored using the specs system. the end point review included the before and after treatment specs score, surgical intervention, and patient satisfaction. potential complications, including cataract development, retinopathy, and tumor formation, were investigated. multivariate analyses were performed to assess the prognostic variables. ## Results: Improvement or resolution was 89% for soft-tissue findings; 70% for proptosis; 85% for extraocular muscle dysfunction;

Who reads Long-term results of irradiation for patients with progressive GRAVES’ ophthalmopathy?

Author

Sheri D Marquez; Bert L Lum; I.Ross McDougall; Shobha Katkuri; Peter S Levin; Michael MacManus; Sarah S Donaldson

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2001

Language

EN

Field

Medicine (Health Sciences)