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Can I read Glutamatergic Control of Dopamine Release During Stress in the Rat Prefrontal Cortex on EtoBox?
Glutamatergic Control of Dopamine Release During Stress in the Rat Prefrontal Cortex by Hank Peter Jedema; Bita Moghaddam is a Neuroscience article available to read on EtoBox.
What is Glutamatergic Control of Dopamine Release During Stress in the Rat Prefrontal Cortex about?
Abstract: In vivo microdialysis was used to assess the hypothesis that the stress‐induced increase in dopamine release in the prefrontal cortex is mediated by stress‐activated glutamate neurotransmission in this region. Local perfusion of an α‐amino‐3‐hydroxy‐5‐methylisoxazole‐4‐propionate (AMPA)/kainate receptor antagonist, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione, blocked the stress‐induced increase in dopamine levels, whereas an NMDA receptor antagonist, 2‐amino‐5‐phosphonopentanoic acid, at the dose tested, was not able to alter this response significantly. These data indicate that the effect of stress on dopamine release in the prefrontal cortex is mediated locally by activation of AMPA/kainate receptors, which modulate the release of dopamine in this region.
Who reads Glutamatergic Control of Dopamine Release During Stress in the Rat Prefrontal Cortex?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Hank Peter Jedema; Bita Moghaddam
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0022-3042)
- Published
- 1994
- Language
- EN
- Field
- Neuroscience (Life Sciences)