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Autacoids are locally acting hormones that are formed in tissues and have complex physiological and pathologic actions. Histamine is a tissue amine released from mast cells that acts on H1, H2, and H3 receptors, causing effects like hypotension, bronchospasm, and pain/itching. Antihistamines block the actions of histamine. Serotonin plays roles in processes like peristalsis and platelet aggregation. Prostaglandins and leukotrienes are synthesized from arachidonic acid and are involved in processes like infl

Author

Manikanta Guptha

Language

EN