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This study establishes a cellular atlas of synovial tissue in children with Juvenile Idiopathic Arthritis (JIA) using advanced profiling techniques. It identifies distinct tissue niches and pathogenic cell populations associated with disease severity and highlights the need for age-specific analyses to improve targeted treatment strategies. The findings underscore the differences in cellular composition between synovial tissue, synovial fluid, and peripheral blood, which may influence therapeutic responses

Author
bushbao1999
Language
EN