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Effects of iodinated contrast and field strength on gadolinium enhancement: Implications for direct MR arthrography by Douglas D. Montgomery; William B. Morrison; Mark E. Schweitzer; Dominik Weishaupt; Lawrence Dougherty is a Medicine article available to read on EtoBox.

What is Effects of iodinated contrast and field strength on gadolinium enhancement: Implications for direct MR arthrography about?

## Abstract ## Purpose To optimize direct magnetic resonance (MR) arthrography by determining the effect of dilution of gadolinium in iodinated contrast, saline, or albumin on T1‐weighted, T2‐weighted, and gradient‐recalled echo (GRE) images, and the effect of scanner field strength. ## Materials and Methods Gadopentetate dimeglumine was diluted into normal saline, albumin, or iodinated contrast (0.625 mmol/liter to 40 mmol/liter). Samples were scanned at 1.5T and 0.2T. Signal intensity was measured using T1‐weighted spin‐echo (SE), T2‐weighted SE, and two‐ and three‐dimensional GRE (20°–75° flip angle) sequences. Graphical analysis of signal intensity vs. gadolinium concentration was performed. ## Results Albumin had no effect on gadolinium contrast. Dilution of gadolinium in iodinated contrast decreased signal intensity on all sequences compared to samples of identical concentration diluted in saline at both 1.5T and 0.2T: with a 2 mmol/liter gadolinium solution at 1.5T, signal was decreased by 26.1% on T1‐weighted images, 31.7% on GRE20 images, and 28.9% on GRE45 images, and the T2 value decreased by 71.1%; at 0.2T, signal was decreased by 23.5% on T1‐weighted images. On all seq

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Author
Douglas D. Montgomery; William B. Morrison; Mark E. Schweitzer; Dominik Weishaupt; Lawrence Dougherty
Publisher
John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-1807)
Published
2002
Language
EN
Field
Medicine (Health Sciences)

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