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The probiotic properties and potential of vaginal Lactobacillus spp. isolated from healthy women against some vaginal pathogens by A. Asadi; V. Lohrasbi; M. Abdi; S. Mirkalantari; M. Esghaei; M. Kashanian; M. Oshaghi; M. Talebi is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
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## Abstract During the last decade, probiotic research has progressed considerably and significant advances have been made in the selection and characterization of specific probiotic strains. The most studied probiotics belong to the genus Lactobacillus. In this study, 80 Lactobacillus spp. isolated from healthy women tolerated low pH and were able to grow in the presence of bile salts. RAPD PCR technique resulted in the identification of 38 different types. These isolates were then evaluated based on adhesion capacity, antibiotic susceptibility and tolerance in simulated gastrointestinal tract. Species-specific PCR and detection of bacteriocin-related genes were also surveyed. Among the isolates, five strains—Lacticaseibacillus rhamnosus NO21, Lacticaseibacillus casei NO1, Lactiplantibacillus plantarum NO4, Lactobacillus acidophilus NO7 and Lactobacillus gasseri NO38—presented acceptable antibiotic susceptibility pattern. Further analysis showed antimicrobial activity of Lacticaseibacillus culture against various bacterial pathogens and real-time PCR showed all five strains were able to prevent the colonization of bacterial pathogens. All five selected strains produced organic aci
Who reads The probiotic properties and potential of vaginal Lactobacillus spp. isolated from healthy women against some vaginal pathogens?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- A. Asadi; V. Lohrasbi; M. Abdi; S. Mirkalantari; M. Esghaei; M. Kashanian; M. Oshaghi; M. Talebi
- Publisher
- Oxford University Press (OUP)
- Published
- 2022
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)