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Insect-Derived Compounds as JAK1 Inhibitors by Jitendra Singh Verma is a document available to read on EtoBox.
This research paper investigates insect-derived semiochemicals from the Formicidae family as potential JAK1 inhibitors through virtual screening and molecular dynamics studies. Out of 1,319 evaluated compounds, six showed significant binding affinity, with 3-Methyl-4-phenylpyrrole demonstrating the strongest interaction compared to the standard inhibitor Abrocitinib. The findings suggest these semiochemicals could serve as innovative alternatives for modulating inflammatory responses, pending further experi
- Author
- Jitendra Singh Verma
- Language
- EN