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CDX-622: Dual Targeting of SCF and TSLP by chukaisioji is a document available to read on EtoBox.
What is CDX-622: Dual Targeting of SCF and TSLP about?
The document discusses the development of the bispecific antibody CDX-622, which targets both mast cells and thymic stromal lymphopoietin (TSLP) to improve treatment for chronic inflammatory conditions. CDX-622 demonstrates significant inhibition of TSLP and stem cell factor (SCF)-dependent inflammatory responses, potentially offering enhanced clinical efficacy compared to single-target therapies. Results indicate that dual neutralization can effectively reduce mast cell numbers and Type 2 inflammation, wit
- Author
- chukaisioji
- Language
- EN