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Can I read Jatropha Neopauciflora Pax Latex Exhibits Wound-Healing Effect in Normal and Diabetic Mice on EtoBox?
Jatropha Neopauciflora Pax Latex Exhibits Wound-Healing Effect in Normal and Diabetic Mice by Hernandez-Hernandez, Ana Bertha (author);Alarcon-Aguilar, Francisco Javier (author);Garcia-Lorenzana, Mario (author);Rodriguez-Monroy, Marco Aurelio (author);Canales-Martinez, Maria Margarita (author) is a Medicine article available to read on EtoBox.
What is Jatropha Neopauciflora Pax Latex Exhibits Wound-Healing Effect in Normal and Diabetic Mice about?
__Jatropha neopauciflora__ is an endemic species of Mexico. Its latex is used to treat wounds, scarring, oral infections, and loose teeth. To date, there are no studies that validate at a morphological level a wound-healing use in diabetes. The present research aimed to evaluate the wound-healing capacity of the latex of __J. neopauciflora__ in the skin of healthy and streptozotocin-induced diabetic mice. Also, a chemical analysis of the latex through molecular exclusion chromatography and HPLC were performed. Male mice (__Mus musculus__) of 7-week-old CD1 strain were used. Groups of healthy and diabetic mice were formed. A longitudinal cut of 1 cm was performed on the depilated skin. All treatments were topically applied to the wound area twice a day for ten days. At the end of the experiments, the skin sections were obtained from the wound area and stained with Hematoxylin-Eosin. Then we counted the number of active fibroblasts in all the experimental groups. In normal mice, the latex accelerated the wound-healing process and decreased the number of active fibroblasts, similarly to Recoveron. In diabetic mice, the latex and Recoveron increased the number of active fibroblasts. In
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- Author
- Hernandez-Hernandez, Ana Bertha (author);Alarcon-Aguilar, Francisco Javier (author);Garcia-Lorenzana, Mario (author);Rodriguez-Monroy, Marco Aurelio (author);Canales-Martinez, Maria Margarita (author)
- Publisher
- SAGE Publications
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)