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Can I read Structural Biology of Endogenous Membrane Protein Assemblies in Native Nanodiscs on EtoBox?
Structural Biology of Endogenous Membrane Protein Assemblies in Native Nanodiscs by Chanelle J. Brown; Catharine Trieber; Michael Overduin is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Structural Biology of Endogenous Membrane Protein Assemblies in Native Nanodiscs about?
The advent of amphiphilic copolymers enables integral membrane proteins to be solubilized into stable 10-30 nm native nanodiscs to resolve their multisubunit structures, post-translational modifications, endogenous lipid bilayers, and small molecule ligands. This breakthrough has positioned biological membrane:protein assemblies (memteins) as fundamental functional units of cellular membranes. Herein, we review copolymer design strategies and methods for the characterization of transmembrane proteins within native nanodiscs by cryo-electron microscopy (cryo-EM), transmission electron microscopy, nuclear magnetic resonance spectroscopy, electron paramagnetic resonance, X-ray diffraction, surface plasmon resonance, and mass spectrometry.
Who reads Structural Biology of Endogenous Membrane Protein Assemblies in Native Nanodiscs?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Chanelle J. Brown; Catharine Trieber; Michael Overduin
- Publisher
- Elsevier BV
- Published
- 2021
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)
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