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What is Development, Structure, and Function of the Tubal Gut about?

Diffuse neuroendocrine system Diffusely dispersed system of peptide hormone-and amine-producing endocrine cells, partly indigenous (e.g., in the digestive tract) and partly derived from the neural crest (e.g., pituitary and adrenal medulla). Microbiome The totality of microorganisms, their genomes and interactions in a particular environment. ## Mucin Specific glycoprotein component of mucus (as in MUC2). Mucus Gel-like substance, covering the surface of the tubal gut and composed of a variety of glycoproteins and proteoglycans. Tubal gut The totality of the lumen forming organs of the digestive tract, including the esophagus, stomach, small and large bowel, appendix, and anus. ## Abbreviations c-Kit Proto-oncogene encoding for the stem cell growth factor receptor Lrg5 Wnt signaling target gene used as a specific marker for gut stem cells MUC2 Mucin specifically expressed in goblet cells of the small and large intestine NET Neuroendocrine tumor Notch Highly conserved signaling pathway involved in intestinal epithelial cell fate regulation Wnt Highly conserved signaling pathway involved in intestinal epithelial stem cell regulation and differentiation RET Proto-oncogene encoding for

Author

F.T. Bosman; P. Yan

Publisher

Elsevier Science & Technology Books

Published

2014

Language

EN

ISBN

9780123864574

Updated

2026-03-24