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The Reliability of Different Formulae to Predict Creatinine Clearance by J. C. Verhave; C. P. Baljé‐Volkers; H. L. Hillege; D. De Zeeuw; P. E. De Jong is a Medicine article available to read on EtoBox.

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**Abstract.** Verhave JC, Baljé‐Volkers CP, Hillege HL, de Zeeuw D, de Jong PE (University Medical Center Groningen, Groningen University, Institute of Drug Exploration, Groningen, the Netherlands). The reliability of different formulae to predict creatinine clearance. __J Intern Med__ 2003; **253**: 563–573. **Objectives.** Creatinine clearance (CCR) is a commonly used tool to measure glomerular filtration rate (GFR) in clinical practice. This tool requires collection of 24‐h urine, which is quite bothersome. Several different formulae have been used to estimate GFR using plasma creatinine and other easy formulae to obtain biometrical data. We examined 10 formulae and compared them with actually measured CCR in a large sample of the general population. **Design.** Cross‐sectional cohort study. **Setting.** University hospital outpatient clinic, a population based study. **Subjects.** A total of 8592 inhabitants of the city of Groningen, 28–75 years of age. The cohort is enriched for microalbuminuria. **Results.** In general, the formulae did not give an accurate estimation of CCR, particularly not in male and in obese subjects. Six formulae, including the Cockcroft–Gault gave a fa

Who reads The Reliability of Different Formulae to Predict Creatinine Clearance?

Author

J. C. Verhave; C. P. Baljé‐Volkers; H. L. Hillege; D. De Zeeuw; P. E. De Jong

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0954-6820)

Published

2003

Language

EN

Field

Medicine (Health Sciences)