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This study presents the preparation of pH-sensitive chiral hydrogels using poly(N-acryloyl-L-alanine) and β-cyclodextrin, which exhibit significant swelling and chiral recognition properties. The hydrogels demonstrate enantiodifferentiating adsorption and release abilities for proline enantiomers, with a preference for L-proline adsorption and D-proline release. These hydrogels have potential applications in chiral drug delivery due to their unique properties and performance.

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2892314325

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EN