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Can I read Model to Determine the Optimal Dietary Elimination Strategy for Treatment of Eosinophilic Esophagitis on EtoBox?
Model to Determine the Optimal Dietary Elimination Strategy for Treatment of Eosinophilic Esophagitis by Tiannan Zhan; Ayman Ali; Jin G. Choi; Minyi Lee; John Leung; Evan S. Dellon; John J. Garber; Chin Hur is a Medicine article available to read on EtoBox.
What is Model to Determine the Optimal Dietary Elimination Strategy for Treatment of Eosinophilic Esophagitis about?
BACKGROUND & AIMS: Q7 Elimination diets are effective treatments for eosinophilic esophagitis (EoE), but foods that activate esophagitis are identified empirically, via a process that involves multiple esophagogastroduodenoscopies (EGDs). No optimized approach has been developed to identify foods that activate EoE. We aimed to compare clinical strategies to provide data to guide treatment. ## METHODS: We developed a computer-based simulation model to determine promising empiric elimination strategies based on reported prevalence values for foods that activate EoE. We conducted a review, searching PubMed through October 1, 2017, for prospective and retrospective studies of EoE and diet. Each patient in our simulated cohort was assigned a profile comprising as many as 12 foods known to induce EoE, including dairy, wheat, eggs, soy, nuts, seafood, beef, corn, chicken, potato, pork, and/or rice. To balance the strategy success rate with the number of EGDs required for food identification, we applied an efficiency frontier approach. Strategies on the frontier were the most efficient, requiring fewer EGDs for higher or equivalent success rates relative to their comparable, neighboring st
Who reads Model to Determine the Optimal Dietary Elimination Strategy for Treatment of Eosinophilic Esophagitis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Tiannan Zhan; Ayman Ali; Jin G. Choi; Minyi Lee; John Leung; Evan S. Dellon; John J. Garber; Chin Hur
- Publisher
- Elsevier Science; Elsevier ; W. B. Saunders Co., Ltd.; Elsevier BV (ISSN 1542-3565)
- Published
- 2018
- Language
- EN
- Field
- Medicine (Health Sciences)