About this Psychology article

Development of criteria for cognitive dysfunction in post-COVID syndrome: the IC-CoDi-COVID approach by Jordi A Matias-Guiu; Elena Herrera; María González-Nosti; Kamini Krishnan; Cristina Delgado-Alonso; María Díez-Cirarda; Miguel Yus; Álvaro Martínez-Petit; Josué Pagán; Jorge Matías-Guiu; José Luis Ayala; Robyn Busch; Bruce P Hermann is a Psychology article available to read on EtoBox.

Background We aimed to develop objective criteria for cognitive dysfunction associated with the post-COVID syndrome. Methods Four hundred and four patients with post-COVID syndrome from two centers were evaluated with comprehensive neuropsychological batteries. The International Classification for Cognitive Disorders in Epilepsy (IC-CoDE) framework was adapted and implemented. A healthy control group of 145 participants and a complementary data-driven approach based on unsupervised machine-learning clustering algorithms were also used to evaluate the optimal classification and cutoff points. Results According to the developed criteria, 41.2% and 17.3% of the sample were classified as having at least one cognitive domain impaired using -1 and -1.5 standard deviations as cutoff points. Attention/processing speed was the most frequently impaired domain. There were no differences in base rates of cognitive impairment between the two centers. Clustering analysis revealed two clusters, although with an important overlap (silhouette index 0.18-0.19). Cognitive impairment was associated with younger age and lower education levels, but not hospitalization. Conclusions We propose a harmoniza

Author

Jordi A Matias-Guiu; Elena Herrera; María González-Nosti; Kamini Krishnan; Cristina Delgado-Alonso; María Díez-Cirarda; Miguel Yus; Álvaro Martínez-Petit; Josué Pagán; Jorge Matías-Guiu; José Luis Ayala; Robyn Busch; Bruce P Hermann

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Psychology (Social Sciences)