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Can I read Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry on EtoBox?
Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry by Colm J. McMahon; Jonathan D. Dodd; Catherine Hill; Neil Woodhouse; Jim M. Wild; Stan Fichele; Charles G. Gallagher; Stephen J. Skehan; Edwin J. R. van Beek; James B. Masterson is a Medicine article available to read on EtoBox.
What is Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry about?
The purpose of this study was to compare hyperpolarized 3helium magnetic resonance imaging ( 3 He MRI) of the lungs in adults with cystic fibrosis (CF) with high-resolution computed tomography (HRCT) and spirometry. Eight patients with stable CF prospectively underwent 3 He MRI, HRCT, and spirometry within 1 week. Three-dimensional (3D) gradient-echo sequence was used during an 18-s breath-hold following inhalation of hyperpolarized 3 He. Each lung was divided into six zones; 3 He MRI was scored as percentage ventilation per lung zone. HRCT was scored using a modified Bhalla scoring system. Univariate (Spearman rank) and multivariate correlations were performed between 3 He MRI, HRCT, and spirometry. Results are expressed as mean±SD (range). Spirometry is expressed as percent predicted. There were four men and four women, mean age=31. 9±9 (20-46). Mean forced expiratory volume in 1 s (FEV) 1 =52%±29 (27-93). Mean 3 He MRI score=74%± 25 (55-100). Mean HRCT score=48.8± 24 (13.5-83). The correlation between 3 He MRI and HRCT was strong (R=±0.89, p<0.001). Bronchiectasis was the only independent predictor of 3 He MRI; 3 He MRI correlated better with FEV 1 and forced vital capacity (FVC
Who reads Hyperpolarized 3helium magnetic resonance ventilation imaging of the lung in cystic fibrosis: comparison with high resolution CT and spirometry?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Colm J. McMahon; Jonathan D. Dodd; Catherine Hill; Neil Woodhouse; Jim M. Wild; Stan Fichele; Charles G. Gallagher; Stephen J. Skehan; Edwin J. R. van Beek; James B. Masterson
- Publisher
- Springer Science and Business Media LLC
- Published
- 2006
- Language
- EN
- Field
- Medicine (Health Sciences)