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Transitioning From Consult-Based to Automatic Pharmacy-Driven Vancomycin Management: Results From a Single, Primary Care Center by Jennifer L. Cole; Russell O’Glee; Michael Clark; Meredith White is a Medicine article available to read on EtoBox.

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## Objective: The transition to area under the curve (AUC) vancomycin monitoring requires substantial updates in pharmacy policies and procedures. The study facility was tasked with transitioning from a consult-based collaborative agreement to an automatic pharmacist management policy on all intravenous (IV) vancomycin orders. The purpose of this quality assessment (QA) study was to evaluate the effectiveness of this transition. Methods: The primary outcome was the proportion of patients with pharmacist assessment of pharmacokinetics and dosing with documentation in IV vancomycin treated patients from January-June 2020. Secondary outcomes included the proportion of AUC 24 levels within therapeutic range, the incidence of acute kidney injury (AKI) and treatment failures in patients treated 72 hours compared to a historical, trough-based cohort. Results: There were 88 patients in the QA analysis with 100% having a pharmacist assessment with documentation. There were 34 patients treated 72 hours in the AUC group, 36 in the trough-based group. AUC 24 fell within desired range in 45% of monitored patients. Rates of AKI (9% vs 11%, p 1⁄4 0.75) and treatment failures were similar (3% vs 0

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Author

Jennifer L. Cole; Russell O’Glee; Michael Clark; Meredith White

Publisher

SAGE Publications

Published

2021

Language

EN

Field

Medicine (Health Sciences)