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Influence of Particle Therapy on Implantable Cardiac Devices: An Experimental Study by Hashimoto, T.; Hashii, H.; Isobe, T.; Ohkawa, A.; Yonai, S.; Matsufuji, N.; Fukuda, S.; Sakae, T.; Aonuma, K.; Sakurai, H. is a Medicine article available to read on EtoBox.

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spatiotemporal dosimetric interplay, two identical polymer gel dosimeters were placed on the 4D motion platform and exposed to a single uniform scanning proton beam with and without motion. A periodic benchmark motion trace (a sine function with 1cm amplitude in SI direction, 4s period) was used to drive the platform. The proton beam range was 20 cm with 10 cm modulation (15 energy layers). A circular brass aperture with 4 cm diameter at isocenter and a Lucite compensator with 2.5cm base and 3.7cm plateau at one quadrant were used to simulate range variations along beam axis due to target motion in and out of the field. A dose of 500 Cobalt-Gray-Equivalent (CGE) was delivered in about 4 min for both static and moving dosimeters. An optical tomography-based laser scanner read out of the irradiated gels yielded 1-mm voxel resolution absorbance values, which were converted to 3D dose matrices using a dose calibration curve. Results: A comparison of dose distributions from the static and dynamic gel deliveries were performed. Profiles along and perpendicular to the central axis for quantitative analysis of dose differences. There was little difference between central axis SOBPs of stat

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Author

Hashimoto, T.; Hashii, H.; Isobe, T.; Ohkawa, A.; Yonai, S.; Matsufuji, N.; Fukuda, S.; Sakae, T.; Aonuma, K.; Sakurai, H.

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2010

Language

EN

Field

Medicine (Health Sciences)