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Early Oncologic Outcomes After Retzius-sparing Versus Anterior Traditional Robot-assisted Radical Prostatectomy by Rossanese, M. (author);Gilante, M. (author);Di Falco, M. (author);Macchione, L. (author);Mucciardi, G. (author);Favilla, V. (author);Ficarra, V. (author) is a nonfiction available to read on EtoBox.

What is Early Oncologic Outcomes After Retzius-sparing Versus Anterior Traditional Robot-assisted Radical Prostatectomy about?

outcomes are: 1) the rate of nerve-sparing approaches within the two groups; 2) 3-, 6-and 12-months IIEF score after surgery. Given the study design and a hypothetical expected difference of 10% between groups, to have adequate statistical power (80%), the required number is 159 patients per group. The trial started on 01/12/2021 and will recruit patients for up to 36 months. Results: At the time of this preliminary analysis (April 2022), 35 patients have been enrolled. Of those, 34 (97%) underwent AR RARP (n = 17, 50%) and standard RARP (n = 17, 50%). Patient (age, BMI, IIEF), disease (PSA, cT, ISUP GG) and mpMRI (PI-RADS score, lesion size) characteristics were similar between groups (all p > 0.05). Median surgical time was superior for AR RARP vs. standard RARP patients (153 vs. 137 mins; p = 0.04). Overall, 4 (23.5%) and 6 (35%) patients had PSM at final pathology in AR-RARP vs. standard RARP groups ( p < 0.001). The rate of bilateral full nerve sparing approaches was similar between the two groups ( p = 0.7). Conclusions: AR RARP and intraoperative frozen section analysis according to AR models appear to reduce the rates of PSMs, relative to standard RARP, in patient candidate

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It is typically read by self-directed learners exploring a subject in depth.

Common subject areas: history, science, philosophy, social sciences.

Author
Rossanese, M. (author);Gilante, M. (author);Di Falco, M. (author);Macchione, L. (author);Mucciardi, G. (author);Favilla, V. (author);Ficarra, V. (author)
Publisher
Elsevier BV
Published
2022
Language
EN
Category
nonfiction

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