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Usefulness of collagen plugging with VasoSeal® after PTCA as compared to manual compression with identical sheath dwell times by Sigmund Silber; Aina Björvik; Holger Mühling; Andreas Rösch is a scholarly article available to read on EtoBox.

What is Usefulness of collagen plugging with VasoSeal® after PTCA as compared to manual compression with identical sheath dwell times about?

This study investigated the usefulness of collagen plugging with VasoSeal in patients after PTCA compared to a control group having identical sheath dwell times and therefore comparable levels of anticoagulation. A total of 150 patients were enrolled in this prospective and randomized study. Sheaths were pulled at exactly 5 h after arterial puncture. Time to hemostasis and local complications were determined. There were no statistical differences in baseline characteristics. The mean time to hemostasis in the collagen group was significantly shorter (3 ؎ 3 min) than that of the control group (17.4 ؎ 7 min). At 24 h, 23% of the collagen group patients had a small, 1% a medium and 4% a large hematoma. In the control group, 32% had a small, 4% a medium sized, but no patient a large hematoma. After collagen, one patient developed a pseudoaneurysm needing vascular surgery. In the control group, no major complication occurred. Compared to patients with manual compression at an identical sheath dwell time and an identical level of anticoagulation, there was a significant reduction in time to hemostasis but no statistical difference regarding local complications. Although the incidence of

Author

Sigmund Silber; Aina Björvik; Holger Mühling; Andreas Rösch

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0098-6569)

Published

1998

Language

EN