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Enhancing Cell-Penetrating Peptides with CX4 by hossain.8304 is a document available to read on EtoBox.
What is Enhancing Cell-Penetrating Peptides with CX4 about?
The study introduces a novel cell-penetrating peptide (CPP) FAM-Y4R4, designed to enhance the delivery of poorly water-soluble drugs like curcumin into cells. By modifying the peptide with p-sulfonatocalix[4]arene (CX4), researchers successfully reduced aggregation, improved solubility, and increased cellular uptake in cancer cell lines MCF7 and A549. The findings suggest that this approach could simplify peptide synthesis and improve drug delivery efficacy for other similar peptides facing aggregation issu
- Author
- hossain.8304
- Language
- EN