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Identifying Potential Surgical Candidates in Patients with Evidence of Bitemporal Epilepsy by Mark D. Holmes; Andrew N. Miles; Carl B. Dodrill; George A. Ojemann; Alan J. Wilensky is a Medicine article available to read on EtoBox.

What is Identifying Potential Surgical Candidates in Patients with Evidence of Bitemporal Epilepsy about?

**Summary:** __Purpose:__ To determine which patients with evidence of medically refractory bitemporal epilepsy are potentially good candidates for surgical therapy. __Methods:__ We reviewed 42 adults with intractable seizures who were found to have bitemporal ictal onsets, based on scalp video‐EEG long‐term monitoring (LTM). All underwent invasive LTM before surgery. Surgical outcomes were classified as seizure free, >75% reduction in seizures, or 75% preponderance of interictal scalp EEG discharges to one temporal region; (b) magnetic resonance imaging (MRI) findings; (c) lateralizing deficits on verbal or visual reproduction memory testing; and (d) memory failure with injection contralateral to side of surgery on Wada testing. __Results:__ Twenty‐six (62%) of 42 patients had unilateral ictal onsets based on intracranial studies. Seizure freedom (occurring in 64% of this group), or >75% seizure reduction (found in 12% of subjects) occurred only when at least one of the following three factors was concordant with the side of surgery: preponderance of interictal scalp EEG discharges, unilateral temporal lesion on MRI, or lateralizing verbal or visual reproduction memory deficits o

Who reads Identifying Potential Surgical Candidates in Patients with Evidence of Bitemporal Epilepsy?

Author

Mark D. Holmes; Andrew N. Miles; Carl B. Dodrill; George A. Ojemann; Alan J. Wilensky

Publisher

Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0013-9580)

Published

2003

Language

EN

Field

Medicine (Health Sciences)