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What is PET Depolymerase Fitness Landscape Analysis about?

This research article details the development of a landscape profiling framework for identifying and engineering polyethylene terephthalate (PET) depolymerases, focusing on the discovery of high-fitness enzyme variants. The study successfully identified the Kubu-PM12 variant, which outperformed benchmarks in harsh industrial conditions, demonstrating significant PET degradation capabilities. Additionally, the framework provides a comprehensive method for exploring the fitness landscape of promiscuous protei

Author

Joseph Hansda

Language

EN