About this document
Evolution of Antidepressant Mechanisms by Lorenzo Gallì is a document available to read on EtoBox.
This review article discusses the evolution of theories about antidepressant mechanisms of action from the 1950s to present. It describes how the initial monoamine theories of depression focused on noradrenaline and then shifted to emphasize serotonin. Current antidepressants aim to increase brain monoamine levels, though some new drugs target downstream effects or novel pathways in an attempt to achieve faster onset of action and broader efficacy. While monoamine drugs remain the standard treatment, the me
- Author
- Lorenzo Gallì
- Language
- EN