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C-Domain ACE and NEP Inhibition in Hypertension by sudarshan.hosmane1995 is a document available to read on EtoBox.
This study investigates a novel antihypertensive therapy combining a C-domain selective ACE inhibitor, lisinopril-tryptophan, with a NEP inhibitor, sacubitril, to treat hypertension. The results show that this combination effectively reduces systolic blood pressure and improves cardiac function without the adverse effects associated with traditional dual inhibitors like omapatrilat. This approach may provide a safer alternative for managing hypertension by targeting specific pathways in the renin-angiotensi
- Author
- sudarshan.hosmane1995
- Language
- EN