Opening book details…
Can I read The effect of adipose-derived stem cells on augmentation ileocystoplasty: A pilot study on EtoBox?
The effect of adipose-derived stem cells on augmentation ileocystoplasty: A pilot study by Ahmed M. Harraz; Guiting Lin; Lia Banie; Guifang Wang; Alan W. Shindel; Yun-Ching Huang; Thomas M. Fandel; Maurice Garcia; Tom F. Lue; Ching-Shwun Lin is a Medicine article available to read on EtoBox.
What is The effect of adipose-derived stem cells on augmentation ileocystoplasty: A pilot study about?
## Objectives Incorporation of intestinal tissue into urinary tract elicits many metabolic and mechanical complications due to anatomical and physiological differences. Adipose-derived stem cells (ADSCs) improve vascularity and functional outcomes by a paracrine mechanism. In a pilot study we investigated whether ADSCs can survive in the augmented bladder and improve its function. ## Materials and methods Autologous ADSCs were harvested from rat paragonadal fat and cultured before injection into a rat model of augmentation ileocystoplasty (study group). Control augmented bladders were injected with cell-free saline. Eight weeks later, rats underwent abdominal ultrasonography for upper tract changes and were examined by conscious cystometry to determine bladder function. After extirpation, augmented bladders were examined using Masson trichrome staining for connective tissue and muscle content, immunohistochemistry for α-smooth muscle actin, and rat endothelial cell antigen staining for endothelial cells. Changes in the extracellular matrix were assessed by determining the elastin content. ADSCs were labelled and tracked by 5-ethynyl-2-deoxyuridine nuclear staining. ## Results Abdom
Who reads The effect of adipose-derived stem cells on augmentation ileocystoplasty: A pilot study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ahmed M. Harraz; Guiting Lin; Lia Banie; Guifang Wang; Alan W. Shindel; Yun-Ching Huang; Thomas M. Fandel; Maurice Garcia; Tom F. Lue; Ching-Shwun Lin
- Publisher
- Informa UK Limited
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)